Online ISSN: 3007-0244,
Print ISSN:  2410-4280
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CHOLANGIOCARCINOMA: RESULTS OF SURGICALTREATMENT
Introduction: Surgical treatment of cholangiocarcinomas is accompanied by a great number of post-operative complications and high mortality. This is due to obstructive jaundice and insufficient liver parenchyma remaining after its extensive resection. The development of irreversible hepatic decompensation in the post-operative period becomes the main cause of unsatisfactory treatment outcomes.
Research aim: to improve the outcomes of the surgical treatment of cholangiocarcinomas using miniinvasive technologies.
Materials and methods: Treatment outcomes for 72 patients with cholangi...
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2016 year | Issue: 6 | Pages: 50-61

СРАВНИТЕЛЬНАЯ ОЦЕНКА ЧАСТОТЫ И СТЕПЕНЕЙ ПОРАЖЕНИЯ КОЖИ ПРИ ГИПОФРАКЦИОНИРОВАННОЙ И ТРАДИЦИОННОЙ ЛУЧЕВОЙ ТЕРАПИИ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ
Актуальность: Лучевая терапия является обязательным шагом для комплексного лечения рака молочной железы. Традиционной схемой лечения является применение 2 Грей за 25 фракций до суммарной очаговой дозы 50 Гр. Но как и любой другой метод лечения, лучевая терапия дает разнообразные побочные эффекты на нормальные ткани в облучаемом поле. Для решения этой проблемы необходимо разработать приемлемые схемы лечения для достижения лучшего локального контроля с минимальным риском для нормальных тканей.
Для сокращения времени лечения были предложены различные послеоперационные  гипофракцио...
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2016 year | Issue: 6 | Pages: 40-49

ANALYSIS OF THE PREVALENCE OF LOW PHYSICAL ACTIVITY AMONG ADOLESCENTS OF THE EAST KAZAKHSTAN REGION
Background. Physical inactivity as a risk factor is associated with obesity and the development of chronic non-communicable diseases such as diabetes and cardiovascular pathology. In most countries, cardiovascular diseases hold the leading place in the structure of mortality and are major cause of disability in the working age population. In Kazakhstan, as in all other regions, there is a rejuvenation of this group of diseases that may be associated with an increase in risk factors in the population.
Materials and methods. We carried out a cross-sectional study 729 adolescents of school ...
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2016 year | Issue: 5 | Pages: 142-149

STRATIFYING THE RISK OF ADVERSE CARDIOVASCULAR EVENTS IN ACUTE MYOCARDIAL INFARCTION WITH ST-SEGMENT ELEVATION
Objective: The aim of our study was to evaluate the prognostic role of β-APM in patients for myocardial infarction with segment elevation ST (STEMI).
Materials and Methods: In the present research, carried out the study of β-adrenoreception erythrocyte membranes (β-APM) in 81 patients with myocardial infarction with ST-segment elevation with a different course of the disease. β-adrenoreactivity of  organism was determined by the value of β-APM using the diagnostic reagent kit "ARM-agate" (LLC "Agat-Med", Moscow). All patients were div...
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2016 year | Issue: 5 | Pages: 131-141

CYTOKINE GENE POLYMORPHISM WITH MYOCARDIAL INFARCTION IN SUBJECTS OF RUSSIAN NATIONALITY
Objective: This article considers the study of the frequency of allelic variants and genotypes of cytokines (TNF-α, IL-10, IL-6) in patients of acute myocardial infarction with segment elevation ST (STEMI) in subjects of Russian nationality.
Materials and Methods: The polymorphism of cytokine genes was examined by restriction analysis of specific areas of the genome amplification products in 41 (69.5%) men and 18 (30.5%) women of Russian nationality. Control group was consisted of 75 healthy subjects (donors of Russian nationality). In all ...
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2016 year | Issue: 5 | Pages: 121-130